microcrystalline cellulose msds fmc

: 1. Material Safety Data Sheet or SDS for Microcrystalline cellulose 9004-34-6 from chemicalbook for download or viewing in the browser. Of all the different brands and grades of MCC, Avicel PH 101 or Emcocel 50 has been the most widely used. Dupont acquired the microcrystalline cellulose business of FMC Corporation in 2017. LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such . MATERIAL SAFETY DATA SHEET Lattice NT Microcrystalline Cellulose MSDS Ref. It does not interfere with other nutrients when added to food products, and is instead, an excellent carrier and stabiliser, helping prolong the viability of food products. >> << These, in turn, are assembled into fibrils in the cell wall. Within the pharmaceuticals field, where the bulk of this material is utilised, Avicel Microcrystalline cellulose functions as a filler and diluent, dry binder, flow, disintegrating, and compression aid in tablets, capsules, and granules. Avicel Microcrystalline cellulose is available in many grades, which differ in particle size, bulk density, and moisture content. Innovation is at the heart of IFFs purpose of applying science and creativity to create a better world. It is highly versatile and is therefore also widely used in topicals and semi-solid & liquid dosage forms, including ointments, creams, gels, pastes, solutions, suspensions, and emulsions. stream %PDF-1.5 IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifiers Product name : Avicel PH-101 Product Number : 11365 Brand : Fluka CAS-No. Avicel PC 611 Microcrystalline Cellulose. 6 0 obj To help, weve put together a simple guide for selecting Avicel Microcrystalline cellulose grades, with simple explanations of some of the most common grades, plus recommendations that will serve the majority of buyers. All Rights Reserved. 1.3. Microcrystalline Cellulose. . Avicel Microcrystalline cellulose is composed of insoluble fibre and does not contribute any other material of nutritional importance. Assay for carboxymethycellulose sodium, wt % 8.3 to 13.8 . Microcrystalline cellulose in certain fiber supplements may cause mild side effects ().These may include gas, bloating and increased stool production.. However, consumption of large quantities of the material may have a laxative effect. /Producer(Sub Systems, Inc.)/CreationDate(D:20181207095625+05'00')/ModDate(D:20181207095625+05'00')/Creator(Sub Systems, Inc.) Material safety data sheet (MSDS) of the m icrocrystalline cellu lose (MCC) <> Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. These include amphiphilicity, a higher degree of crystallinity, surface area, higher hydration properties, and morphology. stream X\o^ The MCC can be synthesized by different processes such as reactive extrusion, enzyme mediated, steam explosion, and acid hydrolysis. Low use levels of GRINDSTED Xanthan Gum are sufficient to provide desired viscosities and textures. Report Category. 1.5% w/w), especially designed for formulating active pharmaceutical ingredients (APIs) with a high sensitivity for moisture. Chemical Formula: (C6H10O5)n 1.4. The product would later go on to be commercialized under the brand name Avicel by FMC Corporation. Microcrystalline cellulose 9004-34-6 <1 Synonyms are provided in Section 1. Avicel is one of the best-known pharmaceutical excipient brands and, without doubt, one of the most frequently used raw materials in solid oral product formulation and manufacture. microcrystalline cellulose and carboxymethylcellulose sodium NF, Ph. The Microcrystalline Cellulose monograph will be incorporated into and become official with the Second Supplement to . If you are already a ChemPoint customer then sign up for access to our online ordering website. Microcrystalline Cellulose E460 MSDS 1. ( . Examination of urine, blood and faecal levels of vitamin B 1 during microcrystalline cellulose ingestion showed no difference from control periods (Anonymous, 1966). The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. 1. LOT #: Available upon request. It is generally regarded as a relatively nontoxic and non-irritant material that is safe for human and animal consumption. : 9004-34-6 1.2 Relevant identified uses of the substance or mixture and uses advised against No. Avicel Microcrystalline Cellulose Physical Properties. They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. There have always been two different points of view for the liquidity of MCC. Production of Pharmaceutical Grade Microcrystalline Cellulose. xv}O2' H~KEe9>G/,:9\i CeolusTM UF-702, MSDS No.060EU MATERIAL SAFETY DATA SHEET NTP: Not listed ACGIH: Not listed 12. If you have Crohn's disease or a history of bowel obstruction, discuss with a doctor or pharmacist about drug interactions with fiber supplements.. Packaging: 34 x 50 kgs fiber drums. Revision No. Avicel co-processed products are high functionality excipients offering improved powder flow, granule properties, tablet compression, and mouth feel. 0.25 - 0.37. It is available in different grades and particle sizes. Origin(s): Plant/Botanical. Microcrystalline Cellulose, Colloidal Silicon Dioxide: 50: 0.20 - 0.30: Best in class binder. An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical tablets, capsules, and granules. This grade of polymer film remains intact at pH< 6, thus protecting the API in gastric environments. These co-processed products are designed to solve complex formulation problems, simplify manufacturing processes, and deliver significant cost savings. SUBSTANCE IDENTIFICATION 1.1. 4 0 obj ChemicalBook. Microcrystalline cellulose (MCC) is one of the most important tableting excipients thanks to its outstanding dry binding properties, enabling the manufacture of tablets by direct compression (DC). 10.1 Future Forecast of the Global Microcrystalline Cellulose Market from 2023-2028 Segment by Region 10.2 Global Microcrystalline Cellulose Production and Growth Rate Forecast by Type (2023-2028 . ( METHOCEL products have been in continuous production for more than 70 years with production facilities and deep product expertise located around the globe. Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. Aquacoat sustained release coating is a pseudo latex aqueous dispersion of water insoluble polymers used for sustained and enteric coating applications. Hi, let us know if you have any questions as you visit our website. Carboxymethyl Cellulose Sodium N/A Nutrition & Biosciences www.pharma.dupont.com HO 00017 - 0 E L 02.2020 www.dupontnutritionandbiosciences.com . 1.3. Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm CAS #: 9004-34-6 . Looking for FMC'searnings news? AFFINISOL hydroxypropyl methylcellulose (HPMC) is a water-soluble cellulosic polymer that can help optimize solubility enhancement of poorly soluble drugs by maintaining stable solid dispersions and inhibiting API crystallization. GRINDSTED Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. ETHOCEL premium ethylcellulose resins are water-insoluble polymers. Browse Avicel PH-101 and related products at MilliporeSigma. ]2}Sb2Wdn-;^}n(/;r\'l3--l~ kuI?H>$7;!l|g|i4&dtb/O3!C!#\qpg+>Q0OM Product and Company Identification Product Name Microcrystalline Cellulose CAS Number 9004-34-6 Parchem - fine & specialty chemicals 415 Huguenot Street New Rochelle, NY 10801 (914) 654-6800 (914) 654-6899 parchem.com info@parchem.com EMERGENCY RESPONSE NUMBER % FMC has deep roots in the food production system worldwide learn more about our latest advances in the future of agriculture. Microcrystalline cellulose has excellent compressibility properties and is widely used in solid forms such as tablets that are hard, but can dissolve quickly, and this has increased its demand in . EMCOCEL 90 M. 130. Aquacoat CPD is an aqueous dispersion of cellulose acetate phthalate used for enteric release applications. 3 0 obj {iy7uEijn0y]"s"gbV~p8Q)zN:cyvs]&,kk=6pcA %iBW|2nKa)Jb7` 0 endstream endobj 524 0 obj 458 endobj 525 0 obj << /Filter /FlateDecode /Length 524 0 R >> stream Tel: 1-239-598-5088 sales@espllc.us www.espllc.us. Manufactured by: China . Find answers in our support articles. : 160182. Explore how you can develop your career and bring your creative ideas to life at IFF. gwf;J(e0o|1p{R~P^);ao!%{0KD7. It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. Alginate drug delivery harnesses the unique properties of seaweed for premier performance in multiple pharmaceutical and nutraceutical applications; they impart viscosity in solutions and even form a three-dimensional gel in the presence of calcium ions. JRS Pharma: PROSOLV SMCC 90: Microcrystalline Cellulose, Colloidal Silicon Dioxide: 125: 0.25 - 0.37: Formulas in which a balance of flow and compaction is required. Your file is uploaded and ready to be published. endobj Microcrystalline Cellulose NF. Microcrystalline cellulose is an exceptional material and one of the most widely used excipients in the pharmaceutical field. %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz United Nations Sustainable Development Goals, Alginates Protanal, Manucol, Protacid and More, Barrier membrane, Controlled release hydrophilic matrix, Taste masking, Carrageenan Gelcarin, Viscarin and More, Controlled release hydrophilic matrix, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Rheology modifier, Rheology modifier/stabilizer, Binder, Controlled release hydrophilic matrix, Rheology modifier, Rheology modifier/stabilizer, Shell - hard capsule, Tablet coatings, Thin films, Topical, Capsules, Other, Solutions, Suspensions, Tablets, Controlled release hydrophilic matrix, Hot melt extrusion, Muco-adhesive, Osmotic pump, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Topical. /Group << /S /Transparency /CS /DeviceRGB /I false /K false >> cas:9000-11-7 msds Carboxymethyl cellulose. Delivering efficient and robust formulations. Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Page 1 of 9. Description: Microcrystalline Cellulose is a term for refined wood pulp manufactured through plant fibre hydrolysis. MSDS Ref. endstream In extrusion-spheronisation, it is the excipient of choice. Aquacoat ECD is an aqueous dispersion of ethylcellulose used for sustained release barrier or slow release pharmaceutical coating, moisture barrier and taste masking applications for tablet and multi-particulate dosage forms. An agricultural sciences company. Our customers around the world enjoy the benefits of TEXTURECEL NaCMC in various wound care products, too. CAS 9004-34-6. 6 Buy Chemicals. l~5C Are you sure you want to delete your template? FMC Corporation. DC remains the most economical technique to produce large batches of tablets, however its efficacy is directly impacted by the raw material attributes. }o]X4]. Safety Data Sheet for Cellulose microcrystalline 102331.

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